| 1 |
Anti-tumor and proapoptotic effect of novel synthetic benzophenone analogues in Ehrlich ascites tumor cells. | Prabhakar BT, Khanum SA, Jayashree K, Salimath BP, Shashikanth S. |
Bioorg Med Chem | 2006 |
| 2 |
Antiangiogenic effect of 2-benzoyl–phenoxy acetamide in EAT cell is mediated by HIF-1α and down regulation of VEGF in-vivo. | Prabhakar BT, Khanum SA, Shashikanth S, Salimath, BP |
Invest New Drugs | 2006 |
| 3 |
Butyrate-induced Proapoptotic and Antiangiogenic pathways in EAT cells require activation of CAD and down-regulation of VEGF | Belakavadi M, Prabhakar BT,Salimath BP |
BiochemBiophys Res Commun | 2005 |
| 4 |
Purification and characterization of butyrate-induced protein phosphatase from EAT cells that is involved in Butyrate-Induced Apoptosis. | Belakavadi M, Prabhakar BT. Salimath. B.P. |
BiochimBiophys Acta. | 2007 |
| 5 |
Butyrate induced phosphatase regulates VEGF and angiogenesis via Sp1. | Prasanna Kumar S, Thippeswamy G, Sheela ML, Prabhakar BT, Salimath, BP |
ArchBiochemBiophys | 2008 |
| 6 |
Evaluation of serum vascular endothelial growth factor (VEGF) and microvessel density (MVD) as prognostic indicators in carcinoma breast. | Shivakumar S, *Prabhakar BT*, Jayashree K, Rajan MG, Salimath BP |
J Cancer Res Clin Oncol | 2008 |
| 7 |
Ca2+ Influx via TRPC Channels Signals Thrombin- Induced NF-κB Activation in Endothelial Cells through AMP-Activated Protein Kinase and Protein Kinase Cδ | Bair AM, *Thippegowda PB*, Freichel M, Ye RD, Cheng N, Vogel SM, Yu Y, Flockerzi V, Malik AB, Tiruppathi C |
J Biol Chem | 2009 |
| 8 |
NF-kB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic by binding to the intronic NF-κB site in the ICAM-1 gene. | Xue J. Thippegowda Prabhakar B, Bachmaier K, Christman JW, Malik AB, Tiruppathi C. |
Physiol Genomics | 2009 |
| 9 |
Inhibition of HIF-1α activity by BP-1 ameliorates adjuvant induced arthritis in rats. | Shankar J, *Thippegowda Prabhakar B*, Kanum SA |
BiochemBiophys Res Commun | 2009 |
| 10 |
Ca2+ influx via TRPC channels induces NF-kB-dependent A20 expression to prevent thrombin-induced apoptosis in endothelial cells. | Thippegowda Prabhakar B, Singh V, Sundivakkam PC, Xue J, Malik AB, Tiruppathi C. |
Am J Physiol Cell Physiol | 2010 |
| 11 |
Synthesis and angiopreventive activity of novel benzophenone- benzimidazole analogues with tumor inhibition effect in mice. | Lakshmi Ranganatha V. Vijay Avin BR., Prabhu T, Prashanth T, Prabhakar B.T., Khanum SA |
Life Sci | 2013 |
| 12 |
Reciprocal Binding of DREAM and USF1 to A20 Promoter Controls A20 Expression. | ChinnaswamyTiruppathi,, Dheeraj Soni,, Dong-Mei Wang,, Jiaping Xue,, Vandana Singh,, Prabhakar B. Thippegowda,, Bopaiah P. Cheppudira,, Rakesh K. Mishra,, Auditi Deb Roy, Zhijian Qian,, Kurt Bachmaier, Youyang Zhao, John W. Christman,, Stephen M. Vogel, Averil Ma, and Asrar B. Malik |
Nat Immunol | 2014 |
| 13 |
Synthesis and tumor inhibitory activity of novel coumarin analogues targeting angiogenesis and apoptosis. | Vijay Avin B.R, Prabhu Thirusangu, AiyeshaFirdouse, Lakshmi Ranganatha V, Prabhakar B.T, Shaukath Ara Khanum |
Eur J Med Chem | 2014 |
| 14 |
New role of lupeol in reticence of angiogenesis, the cellular parameter of neoplastic progression in tumorigenesis models through altered gene expression. | Vijay Avin BR, Prabhu T, Ramesh CK, Vigneshwaran V, Riaz M, Jayashree K, Prabhakar BT |
BiochemBiophys Res Commun | 2014 |
| 15 |
DAO-9 (2,5-di(4-aryloylaryloxymethyl)-1,3,4-oxadiazole) exhibits p53 induced apoptogenesis through Caspase-3 mediated endonuclease activity in murine carcinoma. | Gurupadaswamy HD., Prabhu T, Vijay Avin BR, Vigneshwaran V, Prashanth Kumar MV, Abhishek TS, Shaukath Ara Khanum, Prabhakar BT |
Biomedicine & Pharmacotherapy | 2014 |
| 16 |
The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation. | Tiruppathi, Chinnaswamy, Dheeraj Soni, Dong-Mei Wang, Jiaping Xue, Vandana Singh, Prabhakar B. Thippegowda, Bopaiah P. Cheppudira et al.. |
Nature immunology | 2014 |
| 17 |
Synthesis and evaluation of novel benzophenone-thiazole derivatives as potent VEGF-A inhibitors | Prashanth T, Thirusangu P, Vijay Avin BR, Lakshmi Ranganatha V, Prabhakar BT, Khanum SA. |
Eur J Med Chem | 2014 |
| 18 |
Synthesis of oxadiazole–morpholine derivatives and manifestation of the repressed CD31 Microvessel Density (MVD) as tumoral angiogenic parameters in Dalton’s Lymphoma. | Mohammed Al-Ghorbani, V Vigneshwaran, V Lakshmi Ranganatha, BT Prabhakar,Shaukath Ara Khanum |
Bioorg Chem | 2015 |
| 19 |
Synthesis and antiproliferative acticity of benzophenone tagged pyridine anologues towards activation of CAD mediated nuclear fragmentation in Dalton’s Lymphoma | Mohammed Al-Ghorbani, Prabhu Thirusangu, Gurupadaswamy H.D., Shamanth Neralagundi H.G., Prabhakar B.T and Shaukath Ara Khanum |
Bioorg Chem | 2016 |
| 20 |
Synthesis and an angiolytic role of novel piperazine-benzothiazole analogues on neovascularisation, a chief tumoral parameter in neoplastic development. | Mohammed Al-Ghorbani, Pavankumar G.S, Naveen P, Prabhu Thirusangu, Prabhakar B.T and Shaukath Ara Khanum |
Bioorg Chem | 2016 |
| 21 |
Synthesis and Biological evaluation of Salicylic acid conjugated Isoxazoline analogues on Immune cell Proliferation and Angiogenesis | NaveenPuttaswamy, PavanKumar G.S., Vigneshwaran V., Prabhakar B.T. Shukath Ara Khanum |
Eur J Med Chem | 2016 |
| 22 |
Design and synthesis of diamide-coupled benzophenones as potential anticancer agents | Zabiulla, Shamanth Neralagundi HG, Bushra Begum A, Prabhakar BT, Khanum SA |
Eur J Med Chem | 2016 |
| 23 |
The anti-invasive role of novel synthesized pyridazine hydrazide appended phenoxy acetic acid against neoplastic development targeting matrix metalloproteases | Eissa Mohammed YH, Thirusangu P, Zabiulla, V V, B T Prabhakar, Khanum SA |
Biomed Pharmacother | 2017 |
| 24 |
BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation | Thirusangu P, Vigneshwaran V, Prashanth T, Vijay Avin BR, Malojirao VH, Rakesh H, Khanum SA, Mahmood R, Prabhakar BT |
Angiogenesis | 2017 |
| 25 |
A tumoural angiogenic gateway blocker, Benzophenone-1B represses the HIF-1α nuclear translocation and its target gene activation against neoplastic progression | Thirusangu P, Vigneshwaran V, Ranganatha VL, Vijay Avin BR, Khanum SA, Mahmood R, Jayashree K, Prabhakar BT |
Biochem Pharmacol | 2017 |
| 26 |
Scutellarein antagonizes the tumorigenesis by modulating cytokine VEGF mediated neoangiogenesis and DFF-40 actuated nucleosomal degradation | Thirusangu P, Vigneshwaran V, Vijay Avin BR, Rakesh H, Vikas HM, Prabhakar BT |
BiochemBiophys Res Commun | 2017 |
| 27 |
Synthesis of novel morpholine conjugated benzophenone analogues and evaluation of antagonistic role against neoplastic development. | Al-Ghorbani M, Thirusangu P, Gurupadaswamy HD, Vigneshwaran V, Mohammed YH, Prabhakar BT, Khanum SA |
Bioorg Chem | 2017 |
| 28 |
Immunomodulatory glc/man-directed Dolichos lablab lectin (DLL) evokes anti-tumourresponse in vivo by counteracting angiogenic gene expressions. | Vigneshwaran V, Thirusangu P, Vijay Avin BR, Krishna V, Pramod SN, Prabhakar BT |
Clin Exp Immunol | 2017 |
| 29 |
Design and synthesis of conjugated azo-hydrazone analogues using nano BF3•SiO2 targeting ROS homeostasis in oncogenic and vascular progression. | Zabiulla, Vigneshwaran V, Bushra AB, Pavankumar GS, Prabhakar BT, Khanum SA |
Biomed Pharmacother | 2017 |
| 30 |
Differential genotypical expression of a NEDD9 in normal and tumor tissues: a possible pharmacological target | GS, Pavan Kumar, and Prabahkar BT |
IJBCP | 2018 |
| 31 |
Antitumor Hybrid BT009K Modulates Inflammation Induced Neovascuaralization in Both Tumorigenic and Non-Tumorigenic Model System | Shamanth Neralagundi H.G., Zabiulla, Shaukath Ara Khanum, Manjunatha H., Prabhakar B.T. |
Journal of Applied Pharmaceutical Science | 2018 |
| 32 |
Scientific validation of the usefulness of Withania somnifera Dunal in the prevention and treatment of cancer." | Pavan Kumar Achar, G. S., B. T. Prabhakar, Suresh Rao, Thomas George, Soniya Abraham, Nicole Sequeira, and Manjeshwar Shrinath Baliga |
Anticancer plants: Properties and Application | 2018 |
| 33 |
Protective Effect of Dietary Curcumin and Capsaicin on LPS-Induced Inflammation in Mice | Thriveni Vasanthkumar, Manjunatha Hanumanthappa*, Prabhakar BT |
Pharmacogn J | 2018 |
| 34 |
The Novel 4-Phenyl-2-Phenoxyacetamide Thiazoles modulates the tumor hypoxia leading to the crackdown of neoangiogenesis and evoking the cell death | Mohammed YHE, Malojirao VH, Thirusangu P, Al-Ghorbani M, Prabhakar BT, Khanum SA |
Eur J Med Chem | 2018 |
| 35 |
The tumor antagonistic steroidal alkaloid Solanidine prompts the intrinsic suicidal signal mediated DFF-40 nuclear import and nucleosomal disruption | Malojirao VH, Vigneshwaran V, Thirusangu P, Mahmood R, Prabhakar BT |
Life Sci | 2018 |
| 36 |
Synthesis and amelioration of inflammatory paw edema by novel benzophenone appended oxadiazole derivatives by exhibiting cyclooxygenase-2 antagonist activity | Puttaswamy N, Malojiao VH, Mohammed YHE, Sherapura A, Prabhakar BT, Khanum SA |
Biomed Pharmacother | 2018 |
| 37 |
Synthesis, characterization and tumor inhibitory activity of a novel Pd (ii) complex derived from methanethiol-bridged (2-((1 H-benzo [d] imidazol-2-yl) methylthio)-1 H-benzo [d] imidazol-6-yl)(phenyl) methanone | methanoneKumar, S., Krishnamurthy, G., Bodke, Y. D., Malojirao, V. H., TR, R. N., Kandagalla, S., & Prabhakar, B. T |
New Journal of Chemistry | 2019 |
| 38 |
Synthesis, characterization and tumor inhibitory activity of a novel Pd(II) complex derived from methanethiol-bridged (2-((1H-benzo[d]imidazol-2-yl)methylthio)-1H benzo[d]imidazol-6-yl)(phenyl)methanone | Sunil Kumar N.,a Krishnamurthy G., Yadav D. Bodke, Vikas H. Malojirao, Ravikumar Naik T. R., ShivanandaKandagalla and Prabhakar B. T. |
New Journal of Chemistry | 2019 |
| 39 |
Vimentin and Non-Muscle Myosin IIA are Members of the Neural Precursor Cell Expressed Developmentally Down-Regulated 9 (NEDD9) Interactome in Head and Neck Squamous Cell Carcinoma Cells | Semelakova M, Grauzam S, Prabhakar BT, Tiedeken J, Coaxum S, Neskey DM, Rosenzweig SA |
Transl Oncol | 2018 |
| 40 |
Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma | Prashanth T, Avin BRV, Thirusangu P, Ranganatha VL, Prabhakar BT, Sharath Chandra JNN, Khanum SA |
Biomed Pharmacother | 2019 |
| 41 |
Synthesis, molecular docking, and apoptogenic efficacy of novel Nheterocycle analogs to target B-cell lymphoma 2/X-linked inhibitorsof apoptosis proteins to regress melanoma | ZabiullaZabiulla, Vikas H. Malojirao, Yasser Hussein Eissa Mohammed, Prabhu Thirusangu, B. T. Prabhakar,Shaukath Ara Khanum. |
Medicinal Chemistry Research | 2019 |
| 42 |
A systems biology approach to identify the key targets of curcumin and capsaicin that downregulate pro-inflammatory pathways in human monocytes | BS Sharath, Kandagalla S, H Malojirao V, G S PK, B T Prabhakar, Hanumanthappa M |
Comput Biol Chem | 2019 |
| 43 |
Novel 1,3,4-oxadiazole Targets STAT3 Signaling to Induce Antitumor Effect in Lung Cancer | H Malojirao V, S SGirimanchanaika , MK Shanmugam, A Sherapura , Dukanya , PK Metri , VVigneshwaran , AChinnathambi , SA Alharbi , SRangappa , CD Mohan , Basappa , BT Prabhakar , KS Rangappa |
Biomedicine | 2020 |
| 44 |
Targeting HIF-1α by newly synthesized Indolephenoxyacetamide (IPA) analogs to induce anti-angiogenesis-mediated solid tumor suppression. | Fares Hezam Al-Ostoot , S Ankith , V Vigneshwaran , G Basappa, Vivek H K, Prabhakar B T, Shaukath Ara Khanum |
Pharmacological Reports | 2021 |
| 45 |
Modulation of DNA damage response by targeting ATM kinase using newly synthesized di-phenoxy acetamide (DPA) analogs to induce anti-neoplasia | Fares Hezam Al-Ostoot.Ankith Sherapura. Vikas H. Malojirao. Prabhu Thirasanghu. Tahani I. Al-Muhimeed. Shaukath Ara Khanum. B. T. Prabhakar |
Pharmacological Reports | 2020 |
| 46 |
In silico characterization of a transcript code based screening of Antimicrobial Peptide from Trichogramma chilonis | Sunil S V, Niranjana P, , Kerima O Z, Santosh kumar H S, Prabhakar B T and Pramod S N |
International Journal of Peptide Research and Therapeutics | 2021 |
| 47 |
Anti-neoplastic pharmacophore benzophenone-1 coumarin (BP-1C) targets JAK2 to induce apoptosis in lung cancer | Sherapura A, Malojirao VH, Thirusangu P, Sharath BS, Kandagalla S, Vigneshwaran V, Novak J, Ranganatha L, Ramachandra YL, Baliga SM, Khanum SA, Prabhakar BT |
Apoptosis | 2021 |
| 48 |
Antiproliferative pharmacophore azo-hydrazone analogue BT-1F exerts death signalling pathway targeting STAT3 in solid tumour | Banumathi, Sherapura A, Malojirao VH, Zabiulla, Sharath BS, Thirusangu P, Mahmood R, Kumari NS, Baliga SM, Khanum SA, Prabhakar BT |
Pharmacol Rep | 2022 |
| 49 |
Synthesis, structure analysis, DFT calculations and energy frameworks of new coumarin appended oxadiazoles, to regress ascites malignancy by targeting VEGF mediated angiogenesis | BanumathiZabiullaAnkith SherapuraHussien Ahmed KhameesB.T.PrabhakarShaukath AraKhanum |
Journal of Molecular Structure | 2022 |
| 50 |
Immunoadjuvant and Humoral Immune Responses of Garlic ( Allium sativum L.) Lectins upon Systemic and Mucosal Administration in BALB/c Mice | SD Padiyappa, H.Avalappa , M.Somegowda, S.Sridhara , YPVenkatesh, B.T.Prabhakar ,SN Pramod1, MS Almujaydil , S Shokralla , AMM Abdelbacki , HO Elansary , Ahmed M El-Sabrout , EA Mahmoud |
Molecules | 2022 |
| 51 |
Corosolic Acid Inhibits Secretory Phospholipase A2IIa as an Anti-Inflammatory Function and Exhibits Anti-Tumor Activity in Ehrlich Ascites Carcinoma Bearing Mice | Sophiya P, Krishna Ram H, AS Giresha, Deepadarshan Urs, Sharath R, Narayanappa M., Manjunatha JG, Devaraju KS, Rajkumar SM, Sathisha AD, Prabhakar BT.,Dharmappa KK |
Journal of Inflammation Research | 2022 |
| 52 |
A systems biology investigation of curcumin potency against TGF-β-induced EMT signaling in lung cancer. | Kandagalla S, Sharath BS, Sherapura A, Grishina M, Potemkin V, Lee J, Ramaswamy G, Prabhakar BT, Hanumanthappa M |
3 Biotech | 2022 |
| 53 |
Novel Benzimidazole Derived Imine Ligand and Its Co(III) and Cu(II) Complexes as Anticancer Agents: Chemical Synthesis, DFT Studies, In Vitro and In Vivo Biological Investigations | G P, Revanasiddappa HD, B J, Prabhakar BT, Shivamallu C, Viswanath PM, Achar RR, Silina E, Stupin V, Manturova N, Shati AA, Alfaifi MY, Elbehairi SEI, Armaković SJ, Armaković S, Kollur SP |
Pharmaceuticals | 2023 |
| 54 |
Novel Tetrahydroisoquinoline-4-carboxylates: Design, Synthesis, and Molecular Docking Studies | Devappa Satyanarayan N, Kammathalli Siddappa M, Rahman A, Belur Ningegowda N, Sherapura A, Siddesh BM, Prabhakar BT. |
Matrix-Metalloproteinase Inhibitory Study of Chem Biodivers | 2023 |
| 55 |
Steroidal alkaloid solanidine impedes hypoxia-driven ATM phosphorylation to switch on anti-angiogenesis in lung adenocarcinoma | Ankith Sherapura, B.M. Siddesh, Vikas H. Malojirao, Prabhu Thirusangu, B.R. Vijay Avin, N Suchetha Kumari, Y.L. Ramachandra, B.T. Prabhakar |
phytomedicine | 2023 |
